White Sox vs. Guardians Odds, Prediction, Line: 2022 MLB Picks, Sunday, August 21, Best Bets from Proven Model

The Cleveland Guardians host the Chicago White Sox for a morning game on Sunday. The game is the finale of a three-game weekend at Progressive Field. Sunday’s game is also the last meeting between the AL Central rivals in Cleveland this season. Dylan Cease takes the hill for Chicago against Aaron Civale for Cleveland.

First pitch is at 12:05 pm ET in Cleveland. Caesars Sportsbook lists Chicago as a -125 favorite (risk $125 to win $100) on the moneyline, while the over/under, or the total number of runs Vegas thinks will be scored, is 7.5 to the latest White Sox vs. Before making any Guardians vs. White Sox, be sure to check out the latest MLB predictions and betting tips from SportsLine’s Projection Model.

SportsLine’s projection model simulates every MLB game 10,000 times, and is 300-260 on the best MLB moneyline picks since the start of the 2021 season. This is the same model that linked the 2021 Atlanta Braves at 10-1 as one of the top three bets to win it all last season. Anyone who has followed it has made profitable returns.

Now, the model has set his sights on Guardians vs. White Sox and has revealed their coveted picks and predictions. You can head over to SportsLine to see all of the model’s MLB picks. Here are several MLB odds and trends for White Sox vs. Guardians:

  • White Sox vs. Guardians money line: White Sox -125, Guardians +105
  • White Sox vs. Keepers plus/minus: 7.5 runs
  • White Sox vs. Keepers career line: White Sox -1.5 (+135)
  • CHW: The White Sox are 29-24 in day games
  • CLE: The Guardians are 30-24 in day games
  • White Sox Selections vs. Guardians: Check out the picks at SportsLine

outstanding game | Cleveland Guardians vs. Chicago White Sox

Why you should support the White Sox

Chicago’s projection is boosted by the presence of Dylan Cease as the team’s projected starting pitcher. Cease is enjoying the best season of his career, and the 26-year-old is an American League Cy Young candidate. He has a 2.09 ERA for the season and Cease leads the AL with 11.98 strikeouts per nine innings. Opponents have a .602 OPS against Cease, and he has a 2.12 ERA in three starts against Cleveland in 2022.

Cease’s season-long numbers are strong, but he’s been even better lately, including a recent 14-start stretch in which he allowed one earned run or less in each outing. Cease has a 0.93 ERA since May 29 and has a 1.34 ERA on the road this season. Behind him, Chicago has an above-average bullpen that averages more than a run per inning with a top-five mark in the AL in home run rate.

Why you should support the Guardians

Cleveland’s offense leads the American League in scoring, providing a high baseline in run production. The Rangers are in the top four in the AL in hits, doubles, triples, stolen bases and batting average, and Cleveland is above the AL average in slugging percentage, OPS, on-base percentage and runs scored .

On the run prevention side, the Guardians lean on Aaron Civale, who has been pitching well the past few days. After a rough start to 2022, Civale has a 2.97 ERA over his last eight starts, allowing a .634 OPS over that stretch. Civale has a 2.00 ERA over his last four starts, and his numbers are much better at home than on the road this season. Cleveland’s bullpen is also pretty good, ranking in the top five in the AL in ERA and wins above replacement, and the Guardians are averaging more than one strikeout per inning and more than three strikeouts by walk

How to make Guardians vs. White Sox picks

SportsLine’s model leans on the total, projecting 7.9 combined runs, and says that one side of the money line has all the value. You can only get the MLB model picks at SportsLine.

So who wins White Sox vs. Guardians? And which side has all the value? Visit SportsLine now to find out which side you should jump on, all from the model who crushed his MLB picks, and find out.

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